Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acetohydroxamic acid
Drug ID BADD_D00028
Description Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Indications and Usage Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Marketing Status Prescription
ATC Code G04BX03
DrugBank ID DB00551
KEGG ID D00220
MeSH ID C006358
PubChem ID 1990
TTD Drug ID D0R9BG
NDC Product Code 0178-0500; 73309-355; 49632-170
Synonyms acetohydroxamic acid | N-hydroxyacetamide | N-hydroxyacetamidine | Lithostat | Uronefrex
Chemical Information
Molecular Formula C2H5NO2
CAS Registry Number 546-88-3
SMILES CC(=O)NO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Injury12.01.08.004--Not Available
Lethargy08.01.01.008; 19.04.04.004; 17.02.04.003--
Malaise08.01.01.003--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.01.02.003--
Phlebitis superficial24.05.03.004--Not Available
Pulmonary embolism22.06.02.001; 24.01.06.001--Not Available
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
Renal failure20.01.03.005--Not Available
Reticulocytosis01.07.02.002--Not Available
Tension19.06.02.005--Not Available
Thrombophlebitis24.01.02.001--Not Available
Tremor17.01.06.002--
Vomiting07.01.07.003--
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