| ADR Ontology |
| ADR Term |
Systemic mastocytosis |
| ADR ID |
BADD_A07740 |
| ADR Hierarchy |
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| Description |
A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis. | A form of systemic mastocytosis in which patients have impaired organ functions due to multifocal infiltrates of pathological MAST CELLS in bone marrow, liver, spleen, gastrointestinal tract, or skeletal system. The cytomorphology shows a low to high grade. | A form of systemic mastocytosis in which patients experience no pain. It is characterized by the multifocal mast cell filtrates, mostly in skin and bone marrow (<20% MAST CELLS). It has a low cytomorphological grade. [MeSH] |
| MedDRA Code |
10042949 |
| MeSH ID |
D034721; D034721; D034721
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Systemic mastocytosis | Indolent systemic mastocytosis | Aggressive systemic mastocytosis | Mastocytosis, Systemic | Mastocytoses, Systemic | Systemic Mastocytoses | Systemic Mastocytosis | Systemic Mast-Cell Disease | Mast-Cell Disease, Systemic | Mast-Cell Diseases, Systemic | Systemic Mast Cell Disease | Systemic Mast-Cell Diseases | Aggressive Systemic Mastocytosis | Aggressive Systemic Mastocytoses | Mastocytoses, Aggressive Systemic | Mastocytosis, Aggressive Systemic | Systemic Mastocytoses, Aggressive | Systemic Mastocytosis, Aggressive | Indolent Systemic Mastocytosis | Indolent Systemic Mastocytoses | Mastocytoses, Indolent Systemic | Mastocytosis, Indolent Systemic | Systemic Mastocytoses, Indolent | Systemic Mastocytosis, Indolent |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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