ADR Ontology |
ADR Term |
Dementia with Lewy bodies |
ADR ID |
BADD_A06471 |
ADR Hierarchy |
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Description |
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124) [MeSH] |
MedDRA Code |
10067889 |
MeSH ID |
D020961
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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Synonym |
Diffuse Lewy body disease | Dementia with Lewy bodies | Lewy Body Disease | Diffuse Lewy Body Disease | Lewy Body Dementia | Cortical Lewy Body Disease | Lewy Body Disease, Cortical | Lewy Body Type Senile Dementia | Lewy Body Disease, Diffuse | Dementia, Lewy Body |
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ADR Related Proteins |
Protein Name |
UniProt AC |
TTD Target ID |
Not Available | Not Available | Not Available |
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Drugs Leading to the ADR |
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