Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Tumour necrosis
ADR ID BADD_A05322
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.32      Neoplasm related morbidities
16.32.03      Oncologic complications and emergencies
16.32.03.009      Tumour necrosis
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.02      Non-site specific necrosis and vascular insufficiency NEC
24.04.02.013      Tumour necrosis
Description Not Available
MedDRA Code 10054094
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Tumour necrosis | Tumor necrosis
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Estrogen receptorP03372T89534
Interleukin-1 alphaP01583T16340
p21 proteinP78460Not Available
Protransforming growth factor alphaP01135T00033
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00535Crizotinib--
BADD_D00723Doxorubicin--
BADD_D00785Epirubicin hydrochloride--
BADD_D00858Everolimus--
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01254Lenvatinib--
BADD_D01633Oxaliplatin--
BADD_D01653Paclitaxel--
BADD_D01687Pazopanib--
BADD_D01922Regorafenib--
BADD_D02058Sorafenib--
BADD_D02100Sunitinib--
BADD_D02101Sunitinib malate--
BADD_D02150Temozolomide--
BADD_D02464Fingolimod--
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