| ADR Ontology |
| ADR Term |
Periventricular leukomalacia |
| ADR ID |
BADD_A05157 |
| ADR Hierarchy |
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| Description |
Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1) [MeSH] |
| MedDRA Code |
10052594 |
| MeSH ID |
D007969
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Periventricular leukomalacia | Leukomalacia, Periventricular | Periventricular Leukomalacia | Leukomalacias, Periventricular | Periventricular Leukomalacias | Encephalomalacia, Periventricular | Encephalomalacias, Periventricular | Periventricular Encephalomalacia | Periventricular Encephalomalacias | Leucomalacia, Periventricular | Leucomalacias, Periventricular | Periventricular Leucomalacia | Periventricular Leucomalacias | Neonatal Cerebral Leukomalacia | Cerebral Leukomalacia, Neonatal | Cerebral Leukomalacias, Neonatal | Leukomalacia, Neonatal Cerebral | Leukomalacias, Neonatal Cerebral | Neonatal Cerebral Leukomalacias | Cystic Periventricular Leukomalacia | Cystic Periventricular Leukomalacias | Leukomalacia, Cystic Periventricular | Leukomalacias, Cystic Periventricular | Periventricular Leukomalacia, Cystic | Periventricular Leukomalacias, Cystic |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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