Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Muscle tightness
ADR ID BADD_A04877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.007      Muscle tightness
Description The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation. (Stedman, 25th ed) [MeSH]
MedDRA Code 10049816
MeSH ID D009129
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neck tightness | Perioral tension | Tightness in jaw | Tightness of jaw muscles | Muscle tightness | Tightness of back muscles | Muscle tension | Muscle Tonus | Tonus, Muscle | Muscle Tightness | Tightness, Muscle | Muscular Tension | Tension, Muscular | Muscle Tension | Tension, Muscle
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02337Varenicline--
BADD_D02346Venlafaxine0.000048%
BADD_D02355Vigabatrin0.000423%
BADD_D02371Vortioxetine0.001007%
BADD_D02372Vortioxetine hydrobromide--
BADD_D02393Zolmitriptan0.000677%
BADD_D02394Zolpidem0.000025%
BADD_D02407Upadacitinib--
BADD_D02412Octreotide--
BADD_D02440Lisdexamfetamine0.000188%
BADD_D02452Icatibant-
BADD_D02456Vilazodone0.000703%
BADD_D02464Fingolimod0.006269%
BADD_D02466Levomilnacipran0.000212%
BADD_D02473Sodium chloride--
BADD_D02484Istradefylline0.001431%
BADD_D02491Valbenazine0.004576%
BADD_D02492Deflazacort0.000175%
BADD_D02507Deutetrabenazine0.001830%
BADD_D02510Rucaparib0.000571%
BADD_D02511Siponimod--
BADD_D02550Diroximel fumarate0.001230%
BADD_D02558Gadolinium cation (3+)-
BADD_D02565Lumateperone0.000666%
BADD_D02577Oseltamivir acid0.000843%
BADD_D02580Ozanimod0.000530%
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