Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Post thrombotic syndrome
ADR ID BADD_A04694
ADR Hierarchy
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.01      Non-site specific embolism and thrombosis
24.01.01.019      Post thrombotic syndrome
Description A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing. [MeSH]
MedDRA Code 10048591
MeSH ID D011186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Lipodermatosclerosis | Postphlebitic syndrome | Post phlebitic syndrome | Post thrombotic syndrome | Postphlebitic Syndrome | Postphlebitic Syndromes | Syndrome, Postphlebitic | Syndromes, Postphlebitic | Postphlebitic Disease | Disease, Postphlebitic | Diseases, Postphlebitic | Postphlebitic Diseases | Postphlebitic Ulcer | Postphlebitic Ulcers | Ulcer, Postphlebitic | Ulcers, Postphlebitic
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Thromboxane A2 receptorP21731T76198
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000662%
BADD_D00165Aripiprazole0.000572%
BADD_D01009Gemcitabine0.003996%
BADD_D01250Lasofoxifene--
BADD_D01253Lenalidomide--
BADD_D01954Rivaroxaban0.002320%
BADD_D02031Sitaxentan--
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