Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pulmonary veno-occlusive disease
ADR ID BADD_A03654
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.06      Pulmonary vascular disorders
22.06.03      Vascular pulmonary disorders NEC
22.06.03.003      Pulmonary veno-occlusive disease
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.06      Pulmonary embolism and thrombosis
24.01.06.008      Pulmonary veno-occlusive disease
Description Pathological process resulting in the fibrous obstruction of the small- and medium-sized PULMONARY VEINS and PULMONARY HYPERTENSION. Veno-occlusion can arise from fibrous proliferation of the VASCULAR INTIMA and VASCULAR MEDIA; THROMBOSIS; or a combination of both. [MeSH]
MedDRA Code 10037458
MeSH ID D011668
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Pulmonary veno-occlusive disease | Pulmonary Veno-Occlusive Disease | Diseases, Pulmonary Veno-Occlusive | Pulmonary Veno-Occlusive Diseases | Veno-Occlusive Diseases, Pulmonary | Veno-Occlusive Disease, Pulmonary | Veno Occlusive Disease, Pulmonary | Pulmonary Venoocclusive Disease | Pulmonary Venoocclusive Diseases | Venoocclusive Disease, Pulmonary | Venoocclusive Diseases, Pulmonary | Pulmonary Veno Occlusive Disease
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00100Ambrisentan0.000577%
BADD_D00285Bosentan0.000350%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.000519%
BADD_D00699Docetaxel0.000533%
BADD_D00788Epoprostenol0.000339%
BADD_D01009Gemcitabine0.001066%
BADD_D01135Iloprost0.000097%
BADD_D01336Macitentan0.000226%
BADD_D01478Mitomycin0.001066%
BADD_D02006Selexipag0.000371%
BADD_D02106Tadalafil0.000250%
BADD_D02268Treprostinil0.001484%
The 1th Page    1    Total 1 Pages