Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01962Roflumilast--
BADD_D01964Romidepsin0.000604%
BADD_D01966Ropinirole--
BADD_D01967Ropinirole hydrochloride--
BADD_D01970Rosiglitazone maleate--
BADD_D01971Rosuvastatin--
BADD_D01973Rotigotine--
BADD_D01974Rotigotine hydrochloride--
BADD_D01977Rufinamide--
BADD_D01978Ruxolitinib0.053041%
BADD_D01981Salmeterol--
BADD_D01989Saquinavir mesylate--
BADD_D01992Saxagliptin--
BADD_D01994Scopolamine--
BADD_D01999Secretin--
BADD_D02002Selegiline--
BADD_D02003Selegiline hydrochloride--
BADD_D02006Selexipag0.005634%
BADD_D02007Semaxanib--
BADD_D02010Sertraline--
BADD_D02011Sertraline hydrochloride--
BADD_D02012Sevelamer--
BADD_D02014Sevelamer hydrochloride--
BADD_D02018Sildenafil--
BADD_D02021Siltuximab--
BADD_D02025Simeprevir--
BADD_D02026Simvastatin0.000856%
BADD_D02027Sincalide0.000385%
BADD_D02029Sitagliptin--
BADD_D02031Sitaxentan--
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ADReCS-Target
ADR Term Drug Name Target