Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01217Itraconazole--
BADD_D01218Ivabradine0.002410%
BADD_D01221Ivermectin--
BADD_D01222Ixabepilone--
BADD_D01223Ixazomib0.019655%
BADD_D01225Kadain--
BADD_D01230Ketoconazole0.000653%
BADD_D01231Ketoprofen--
BADD_D01233Ketorolac tromethamine--
BADD_D01236Labetalol--
BADD_D01237Labetalol hydrochloride--
BADD_D01238Lacosamide--
BADD_D01240Lactulose0.000939%
BADD_D01241Lamisil--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine--
BADD_D01244Lanreotide acetate--
BADD_D01245Lansoprazole--
BADD_D01248Lapatinib0.004757%
BADD_D01250Lasofoxifene--
BADD_D01252Leflunomide--
BADD_D01253Lenalidomide2.098306%
BADD_D01254Lenvatinib0.016946%
BADD_D01255Lercanidipine--
BADD_D01257Letrozole--
BADD_D01258Leucovorin0.009293%
BADD_D01259Leucovorin calcium--
BADD_D01260Leuprolide acetate0.339292%
BADD_D01261Leuprolide monoacetate--
BADD_D01265Levetiracetam--
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ADReCS-Target
ADR Term Drug Name Target