Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fanconi syndrome
ADR ID BADD_A01620
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.06      Renal and urinary tract disorders congenital
03.06.01      Renal disorders congenital
03.06.01.001      Fanconi syndrome
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.01      Metabolic acidoses (excl diabetic acidoses)
14.01.01.011      Fanconi syndrome
20      Renal and urinary disorders
20.05      Nephropathies
20.05.03      Nephropathies and tubular disorders NEC
20.05.03.009      Fanconi syndrome
Description A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA. [MeSH]
MedDRA Code 10016219
MeSH ID D005198
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
De Toni-Fanconi syndrome | Fanconi syndrome | Fanconi syndrome congenital | Fanconi Syndrome | Syndrome, Fanconi | Proximal Renal Tubular Dysfunction | Toni-Debre-Fanconi Syndrome | Primary Toni-Debre-Fanconi Syndrome | Neonatal De Toni-Debre-Fanconi Syndrome | De Toni-Debre-Fanconi Syndrome | Idiopathic De Toni-Debre-Fanconi Syndrome | Fanconi Bickel Syndrome | Bickel Syndrome, Fanconi | Syndrome, Fanconi Bickel | Fanconi-Bickel Syndrome | Fanconi-Bickel Syndromes | Syndrome, Fanconi-Bickel | Syndromes, Fanconi-Bickel | Glycogen Storage Disease XI | Pseudo-Phlorizin Diabetes | Diabete, Pseudo-Phlorizin | Diabetes, Pseudo-Phlorizin | Pseudo Phlorizin Diabetes | Pseudo-Phlorizin Diabete | Hepatic Glycogenosis with Amino Aciduria and Glucosuria | Hepatic Glycogenosis with Fanconi Nephropathy | Hepatorenal Glycogenosis with Renal Fanconi Syndrome | Lignac-Fanconi Syndrome | Lignac Fanconi Syndrome | Syndrome, Lignac-Fanconi | Fanconi Syndrome with Intestinal Malabsorption and Galactose Intolerance | Glycogenosis, Fanconi Type | Fanconi Type Glycogenosis | Fanconi Syndrome without Cystinosis | Renal Fanconi Syndrome | Fanconi Syndrome, Renal | Syndrome, Renal Fanconi | Luder-Sheldon Syndrome | Luder Sheldon Syndrome | Syndrome, Luder-Sheldon | Adult Fanconi Syndrome | Fanconi Syndrome, Adult | Syndrome, Adult Fanconi | Fanconi Renotubular Syndrome | Renotubular Syndrome, Fanconi | Syndrome, Fanconi Renotubular
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00043Adefovir--
BADD_D00044Adefovir dipivoxil0.028209%
BADD_D00344Canagliflozin0.001149%
BADD_D00364Carboplatin0.001598%
BADD_D00463Cidofovir--
BADD_D00488Clobazam0.000602%
BADD_D00594Deferasirox0.026240%
BADD_D00696Divalproex sodium--
BADD_D00749Efavirenz--
BADD_D00766Emtricitabine0.008555%
BADD_D01133Ifosfamide--
BADD_D01204Isoniazid0.025481%
BADD_D01242Lamivudine0.004638%
BADD_D01253Lenalidomide--
BADD_D01752Phenobarbital0.001490%
BADD_D01835Pregabalin0.000236%
BADD_D01952Ritonavir0.005050%
BADD_D02010Sertraline0.000212%
BADD_D02154Tenofovir--
BADD_D02155Tenofovir disoproxil0.022215%
BADD_D02156Tenofovir disoproxil fumarate--
BADD_D02329Valproic acid0.004207%
BADD_D02392Zoledronic acid0.039365%
BADD_D02396Zonisamide0.003938%
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