Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxygen
Drug ID BADD_D02471
Description Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Indications and Usage Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
Marketing Status Not Available
ATC Code V03AN01
DrugBank ID DB09140
KEGG ID D00003
MeSH ID D010100
PubChem ID 977
TTD Drug ID Not Available
NDC Product Code 71408-001; 76091-002; 49154-001; 55703-001; 62377-001; 53952-001; 11928-002; 62671-001; 52568-001; 43621-001; 60367-002; 64395-0001; 57999-001; 72760-001; 68623-123; 59387-001; 51319-072; 53663-0001; 62066-001; 49221-0030; 66083-741; 82401-001; 60768-001; 51486-720; 67061-001; 62234-001; 51319-073; 61865-001; 62686-001; 55913-001; 73055-001; 60596-1072; 56130-002; 61830-001; 49204-001; 72457-003; 10297-001; 44517-001; 42821-001; 11054-009; 29181-001; 62481-4565; 61420-0001; 20942-672; 69024-001; 62914-1000; 19218-0005; 58049-123; 69216-001; 70951-123; 54451-001; 59788-001; 45405-001; 70323-123; 72661-123; 19218-0002; 67525-100; 59247-001; 63674-001; 65603-100; 65336-001; 19218-0004; 62118-001; 73266-001; 59087-001; 14214-0123; 62486-130; 63560-001; 72692-123; 66586-1073; 69534-001; 60568-123; 58722-9094; 64075-123; 10482-002; 10412-0001; 39313-001; 68877-001; 10073-111; 61776-0001; 58632-001; 25373-001; 54182-001; 10526-005; 65077-001; 65297-001; 80268-001; 72746-0001; 62273-001; 72807-001; 81313-001; 63970-001; 52698-001; 44076-010; 15055-001; 60980-002; 61398-0828; 55728-100; 48546-0006; 51475-001; 81734-001; 50153-110; 55151-123; 51887-720; 14080-001; 63144-001; 46123-001; 58089-001; 49575-001; 42068-001; 61362-2150; 58700-001; 49479-722; 66228-001; 61426-123; 19218-0001; 65386-0001; 57957-0007; 69241-001; 11988-001; 58125-0001; 24887-001; 13826-001; 52374-011; 60971-1176; 46123-045; 62715-0001; 73012-001; 61128-001; 62179-1234; 59579-001; 19218-0008; 10698-0001; 64140-101; 55785-123; 52374-101; 19979-000; 80792-001; 63862-011; 67932-1313; 48546-0002; 66754-001; 54316-123; 20703-002; 67573-0104; 10942-2001; 62598-001; 68769-002; 72574-001; 76349-001; 81676-001; 76831-001; 49798-001; 67905-0001; 42914-001; 70097-001; 11324-721; 51051-003; 11401-6994; 17575-001; 10690-001; 58247-001; 72817-001; 44363-1815; 80421-100; 58128-0001; 62097-9937; 50505-001; 73468-005; 63553-001; 19218-0009; 50699-1072; 54706-0001; 67477-001; 66890-990; 65868-001; 23650-001; 63418-0001; 13859-001; 54202-001; 60779-001; 43734-002; 50322-005; 52003-011; 66767-999; 55858-001; 73422-001; 72713-123; 62447-0011; 54384-1073; 69075-001; 60184-001; 64545-0001; 52374-001; 59842-012; 10221-001; 58755-0001; 62581-1234; 19218-0006; 50597-001; 72987-001; 43734-001; 53854-123; 72814-001; 10492-001; 73037-001; 72995-001; 49799-001; 73078-001; 20479-0682; 59378-001; 80650-001; 42602-001; 60833-001; 66503-001; 64952-002; 60849-123; 61580-123; 81681-001; 21220-119; 64464-001; 63138-120; 63978-001; 73073-001; 40097-001; 71227-001; 70313-001; 70291-1000; 58662-0001; 43713-001; 68317-001; 72908-001; 54619-0001; 72710-123; 76056-001; 55037-113; 53425-001; 67711-001; 42887-001; 61903-001; 70300-001; 72973-001; 72637-001; 58722-9093; 54832-0001; 68794-001; 61869-0001; 54218-500; 58878-001; 65010-001; 11324-001; 66961-100; 66345-001; 24312-001; 20175-072; 26866-001; 59336-001; 68540-001; 31462-001; 62371-1234; 66487-001; 18482-018; 55322-0001; 73087-001; 19218-0003; 34940-004; 65208-123; 63173-001; 46123-002; 73093-001; 72706-123; 60560-1072; 70977-001; 81700-001; 64097-0001; 42241-001; 72862-001; 81287-001; 59924-001; 51960-001; 73543-001; 55050-0011; 64203-020; 64920-0001; 52142-001; 59522-001; 11056-001; 50063-001; 72662-123; 69286-001; 10218-001; 68796-5626; 52346-013; 65464-001; 49653-003; 44356-0001; 67506-001; 82007-000; 65257-001; 14784-001
Synonyms Oxygen | Oxygen-16 | Oxygen 16 | Dioxygen
Chemical Information
Molecular Formula O2
CAS Registry Number 7782-44-7
SMILES O=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bronchopleural fistula22.05.03.0010.005831%
Cluster headache17.14.01.0030.005831%Not Available
Hepatic enzyme increased13.03.01.0190.003803%Not Available
Cardiac disorder02.01.01.0030.002282%Not Available
Respiratory fume inhalation disorder12.03.02.003; 22.02.07.0090.005831%Not Available
Respiratory tract infection22.07.07.001; 11.01.08.0170.005831%Not Available
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.001521%Not Available
Acute kidney injury20.01.03.0160.011662%
Multiple organ dysfunction syndrome08.01.03.0570.002282%
Pneumocephalus17.02.05.060; 12.02.04.0090.005831%Not Available
Oxygen consumption decreased13.02.01.0260.005831%Not Available
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