Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasagiline
Drug ID BADD_D02441
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status Not Available
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D08469
MeSH ID C031967
PubChem ID 3052776
TTD Drug ID D06OMW
NDC Product Code 42291-779; 67877-259; 47781-690; 0093-3061; 67877-260; 42291-780; 47781-683; 42571-220; 16714-771; 16714-770; 0093-3060; 42571-221
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C12H13N
CAS Registry Number 136236-51-6
SMILES C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Mobility decreased17.02.05.018; 15.03.01.003; 08.01.03.0300.014884%Not Available
Musculoskeletal disorder15.03.01.0040.007442%Not Available
Abasia17.02.05.035; 08.01.02.0070.007442%Not Available
Shock haemorrhagic14.05.05.003; 24.06.02.0140.007442%Not Available
Balance disorder17.02.02.0070.018605%Not Available
Sudden onset of sleep17.15.04.0030.026047%Not Available
Dysstasia17.02.02.0120.007442%Not Available
Contusion24.07.06.001; 23.03.11.002; 15.03.01.008; 12.01.06.0010.011163%
Lower gastrointestinal haemorrhage24.07.02.030; 07.12.02.0070.001941%
Musculoskeletal stiffness15.03.01.0050.007442%Not Available
Faecaloma07.01.03.0040.007442%Not Available
Cognitive disorder17.03.03.003; 19.21.02.0010.022326%
Prostate cancer21.04.02.002; 16.25.01.0010.001941%Not Available
Freezing phenomenon17.01.05.0060.014884%Not Available
Impulse-control disorder19.18.01.0020.033489%Not Available
Ischaemic stroke24.04.06.010; 17.08.01.0180.007442%Not Available
Motor dysfunction17.02.10.0040.007442%Not Available
Cardiac valve disease02.07.02.0010.007442%Not Available
Decreased appetite14.03.01.005; 08.01.09.0280.026047%
Parkinson's disease17.01.05.0100.012619%Not Available
Disease progression08.01.03.038--
Psychotic disorder19.03.01.0020.011163%
Hypophagia19.09.01.004; 14.03.01.006; 07.01.06.0100.007442%Not Available
Cerebral hypoperfusion12.02.01.014; 24.03.05.008; 17.08.02.0110.007442%Not Available
Hypersexuality19.08.03.0050.018605%Not Available
Acute kidney injury20.01.03.016--
Gambling disorder19.07.02.0140.018605%Not Available
Ilium fracture15.08.06.002; 12.04.06.0020.007442%Not Available
Impulsive behaviour19.18.01.0010.018605%Not Available
Jealous delusion19.10.01.0060.007442%Not Available
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