Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasagiline
Drug ID BADD_D02441
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status Not Available
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D08469
MeSH ID C031967
PubChem ID 3052776
TTD Drug ID D06OMW
NDC Product Code 42291-779; 67877-259; 47781-690; 0093-3061; 67877-260; 42291-780; 47781-683; 42571-220; 16714-771; 16714-770; 0093-3060; 42571-221
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C12H13N
CAS Registry Number 136236-51-6
SMILES C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cough22.02.03.001--
Death08.04.01.0010.024268%
Decubitus ulcer23.03.11.0060.007442%Not Available
Dehydration14.05.05.0010.022326%
Delusion19.10.01.0010.007442%
Dementia19.20.02.001; 17.03.01.0010.002912%Not Available
Depressed level of consciousness17.02.04.0020.014884%
Depression19.15.01.0010.018605%
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.033489%
Dysarthria19.19.03.001; 17.02.08.0010.007442%
Dyskinesia17.01.02.0060.040931%
Dysphagia07.01.06.0030.026047%
Dyspnoea22.02.01.004; 02.01.03.002--
Dystonia17.01.03.0010.014884%Not Available
Dysuria20.02.02.0020.007442%
Emotional disorder19.04.02.0050.007442%Not Available
Epilepsy17.12.03.0020.007442%Not Available
Fatigue08.01.01.002--
Fracture15.08.02.001; 12.04.02.0010.037210%
Gait disturbance08.01.02.002; 17.02.05.0160.014884%
Gastric ulcer07.04.03.0020.011163%
Haematoma24.07.01.0010.007442%
Hallucination19.10.02.0020.070700%
Hallucination, auditory19.10.02.0030.007442%Not Available
Hallucination, visual19.10.02.0040.044652%Not Available
Headache17.14.01.001--
Hepatitis09.01.07.0040.007442%Not Available
Hip fracture15.08.03.001; 12.04.01.0010.007442%
Hyperhidrosis23.02.03.004; 08.01.03.0280.011163%
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