Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Enoxaparin
Drug ID BADD_D02438
Description Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Indications and Usage For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Marketing Status Not Available
ATC Code B01AB01; B01AB12; C05BA03; S01XA14
DrugBank ID DB01225
KEGG ID D07510
MeSH ID D017984
PubChem ID 772
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Enoxaparin | Enoxaparine | PK-10,169 | PK 10,169 | PK10,169 | PK-10169 | PK 10169 | PK10169 | EMT-967 | EMT 967 | EMT967 | Lovenox | Clexane | EMT-966 | EMT 966 | EMT966
Chemical Information
Molecular Formula C26H42N2O37S5
CAS Registry Number 9005-49-6
SMILES CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C( C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fungal infection11.03.05.001--Not Available
Gait disturbance17.02.05.016; 08.01.02.002--
Gamma-glutamyltransferase increased13.03.01.0110.003673%
Gastric haemorrhage24.07.02.007; 07.12.01.0010.001574%
Gastric ulcer07.04.03.0020.001049%
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.0090.007346%Not Available
Gastrointestinal necrosis24.04.08.006; 07.15.01.0030.002099%
Generalised tonic-clonic seizure17.12.01.002--Not Available
Gingival bleeding24.07.02.010; 07.09.07.0010.000274%Not Available
Groin pain15.03.02.0040.000274%Not Available
Haemarthrosis24.07.01.046; 15.01.01.004; 12.04.03.0010.000411%Not Available
Haematemesis24.07.02.011; 07.12.02.0020.002623%Not Available
Haematochezia24.07.02.012; 07.12.02.0030.001574%Not Available
Haematocrit decreased13.01.05.0010.005247%Not Available
Haematoma24.07.01.0010.032005%
Haematuria24.07.01.047; 20.02.01.0060.008395%
Blood urine present13.13.02.0020.001574%Not Available
Haemoglobin decreased13.01.05.0030.018888%Not Available
Haemolytic anaemia01.06.03.0020.002099%Not Available
Haemoptysis02.01.02.006; 24.07.01.006; 22.02.03.0040.002623%Not Available
Haemorrhage intracranial24.07.04.003; 17.08.01.0080.000547%
Haemorrhage subcutaneous24.07.06.010; 23.06.07.0020.001049%Not Available
Haemorrhagic stroke24.07.04.014; 17.08.01.0110.000821%Not Available
Headache17.14.01.001--
Heart rate abnormal13.14.04.0060.001049%Not Available
Heart rate increased13.14.04.002--Not Available
Hemiparesis17.01.04.0010.003148%
Hemiplegia17.01.04.0020.000274%Not Available
Hepatic cirrhosis09.01.04.0010.000274%Not Available
Hepatic function abnormal09.01.02.001--Not Available
The 5th Page    First    Pre   5 6 7 8 9    Next   Last    Total 16 Pages