Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Enoxaparin
Drug ID BADD_D02438
Description Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Indications and Usage For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Marketing Status Not Available
ATC Code B01AB01; B01AB12; C05BA03; S01XA14
DrugBank ID DB01225
KEGG ID D07510
MeSH ID D017984
PubChem ID 772
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Enoxaparin | Enoxaparine | PK-10,169 | PK 10,169 | PK10,169 | PK-10169 | PK 10169 | PK10169 | EMT-967 | EMT 967 | EMT967 | Lovenox | Clexane | EMT-966 | EMT 966 | EMT966
Chemical Information
Molecular Formula C26H42N2O37S5
CAS Registry Number 9005-49-6
SMILES CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C( C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.003148%
Abdominal pain07.01.05.0020.014691%
Abdominal pain lower07.01.05.0100.001574%Not Available
Abdominal pain upper07.01.05.003--
Abdominal rigidity07.01.05.0110.000274%Not Available
Abdominal tenderness07.01.05.0040.002623%Not Available
Abortion18.01.01.0010.001049%Not Available
Abortion spontaneous18.01.04.0010.005247%Not Available
Abscess11.01.08.0010.001049%Not Available
Activated partial thromboplastin time prolonged13.01.02.0010.002623%
Acute hepatic failure09.01.03.0010.000274%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Acute prerenal failure24.06.02.003; 20.01.03.0010.001574%Not Available
Adrenal haemorrhage24.07.01.023; 12.01.02.006; 05.01.03.0020.001574%Not Available
Adrenal insufficiency14.11.01.004; 05.01.02.0010.001049%
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.0010.006821%Not Available
Alanine aminotransferase increased13.03.01.0030.004197%
Altered state of consciousness19.07.01.003; 17.02.04.001--Not Available
Alveolitis allergic22.01.01.002; 10.01.03.0080.000274%Not Available
Anaemia01.03.02.0010.029382%
Anaphylactic shock10.01.07.002; 24.06.02.0040.001574%Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.0030.000274%Not Available
Angioedema23.04.01.001; 10.01.05.0090.005771%Not Available
Anuria20.01.03.0020.002099%Not Available
Anxiety19.06.02.002--
Aortic thrombosis24.01.09.0010.001574%Not Available
Aphasia19.21.01.001; 17.02.03.001--
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