Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Remifentanil
Drug ID BADD_D02430
Description Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Indications and Usage For use during the induction and maintenance of general anesthesia.
Marketing Status Not Available
ATC Code N01AH06
DrugBank ID DB00899
KEGG ID D08473
MeSH ID D000077208
PubChem ID 60815
TTD Drug ID D0T5OX
NDC Product Code Not Available
Synonyms Remifentanil | 3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester | Remifentanil Hydrochloride | Ultiva | Remifentanil Monohydrochloride | GI 87084B | GI87084B | GI-87084B
Chemical Information
Molecular Formula C20H28N2O5
CAS Registry Number 132875-61-7
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.0010.001970%
Anaphylactic shock24.06.02.004; 10.01.07.0020.005911%Not Available
Blood pressure decreased13.14.03.0020.001576%Not Available
Bronchospasm22.03.01.004; 10.01.03.0120.000788%
Pain08.01.08.0040.001182%
Tachycardia02.03.02.0070.001576%Not Available
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