| Drug Name |
Norethisterone |
| Drug ID |
BADD_D02427 |
| Description |
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol].[A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications including contraception and hormone replacement therapy.[L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use as an oral contraceptive until 1962.[L10439] |
| Indications and Usage |
For the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer. |
| Marketing Status |
Not Available |
| ATC Code |
G03AC01; G03DC02 |
| DrugBank ID |
DB00717
|
| KEGG ID |
D00182
|
| MeSH ID |
D009640
|
| PubChem ID |
6230
|
| TTD Drug ID |
D0GL7U
|
| NDC Product Code |
12866-1013; 73774-005 |
| Synonyms |
Norethindrone | Norpregneninolone | Norethisterone | 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)- | Ethinylnortestosterone | Conceplan | Micronor | Norlutin | Nor-QD | Nor QD | NorQD | Norcolut | Norcolute | Norethindrone, (1 beta)-Isomer | Monogest |
