Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Foscarnet
Drug ID BADD_D02421
Description An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Indications and Usage For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.
Marketing Status Not Available
ATC Code J05AD01
DrugBank ID DB00529
KEGG ID D00579
MeSH ID D017245
PubChem ID 3415
TTD Drug ID D0OT0O
NDC Product Code Not Available
Synonyms Foscarnet | Phosphonoformic Acid | Foscarnet Trisodium Salt | Foscarnet Calcium (2:3) Salt | Foscarnet Disodium Salt | Foscarnet Magnesium (2:3) Salt | Trisodium Phosphonoformate | Phosphonoformate | Foscarnet Sodium | Foscarnet Trilithium Salt | Foscarnet Tripotassium Salt | Foscarnet Sodium Hexahydrate | Foscavir | Foscarnet Barium (2:3) Salt | Foscarnet Manganese (2+) (2:3) Salt
Chemical Information
Molecular Formula CH3O5P
CAS Registry Number 4428-95-9
SMILES C(=O)(O)P(=O)(O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute respiratory distress syndrome22.01.03.0010.000566%
Altered state of consciousness17.02.04.001; 19.07.01.0030.000566%Not Available
Blood creatinine increased13.13.01.0040.002170%
Cardiac arrest02.03.04.0010.000377%
Cystitis haemorrhagic20.03.02.0030.001447%Not Available
Cytomegalovirus infection11.05.01.0020.004340%
Dermatomyositis10.04.02.001; 23.03.02.001; 15.05.01.0020.001447%Not Available
Diarrhoea07.02.01.001--
Dysuria20.02.02.0020.001447%
Electrolyte imbalance14.05.01.0020.001447%Not Available
Encephalitis viral17.06.06.002; 11.05.04.0100.000377%Not Available
Haematuria24.07.01.047; 20.02.01.0060.001447%
Headache17.14.01.001--
Hepatic failure09.01.03.0020.000755%
Human herpesvirus 6 infection11.05.02.0200.000566%Not Available
Hypocalcaemia14.04.01.0040.005787%
Hypokalaemia14.05.03.0020.006510%
Hypomagnesaemia14.04.02.0010.002893%
Hypophosphataemia14.04.03.0010.002170%
Interstitial lung disease22.01.02.003; 10.02.01.0330.000377%Not Available
Neuropathy peripheral17.09.03.0030.001447%Not Available
Pancreatitis07.18.01.0010.001447%
Pancytopenia01.03.03.0030.000566%Not Available
Paraesthesia17.02.06.0050.002170%
Pneumonia11.01.09.003; 22.07.01.0030.000566%Not Available
Polyneuropathy17.09.03.0120.001447%Not Available
Pulmonary oedema22.01.03.003; 02.05.02.0030.000377%
Renal failure20.01.03.0050.002076%Not Available
Renal tubular acidosis20.05.03.003; 14.01.01.0050.002170%Not Available
Renal tubular disorder20.05.03.0040.002893%Not Available
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