Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Valganciclovir
Drug ID BADD_D02326
Description Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Indications and Usage Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections.
Marketing Status Prescription
ATC Code J05AB14
DrugBank ID DB01610
KEGG ID D02495
MeSH ID D000077562
PubChem ID 135413535
TTD Drug ID D06GWF
NDC Product Code 55111-762; 60429-846; 63739-076; 27241-158; 16714-765; 70010-051; 0004-0038; 50268-787; 71151-003; 31722-832; 69097-277; 0904-6796; 48433-124; 68084-965; 70069-810
Synonyms Valganciclovir | Ganciclovir L-valyl Ester | Ganciclovir L valyl Ester | Valcyt | Valganciclovir Hydrochloride | Valcyte
Chemical Information
Molecular Formula C14H22N6O5
CAS Registry Number 175865-60-8
SMILES CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Myoclonus17.02.05.008--Not Available
Nasal congestion22.04.04.001--
Nasopharyngitis22.07.03.002; 11.01.13.0020.004896%Not Available
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
Neoplasm malignant16.16.01.0010.001277%Not Available
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.0030.004896%Not Available
Neutropenia01.02.03.0040.022030%Not Available
Neutrophil count decreased13.01.06.0100.004896%
Night sweats23.02.03.006; 08.01.03.031--Not Available
Oedema14.05.06.010; 08.01.07.0060.004896%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oesophageal candidiasis11.03.03.008; 07.19.06.001--Not Available
Oesophagitis07.08.05.001--
Oral candidiasis11.03.03.004; 07.05.07.001--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.0030.001916%Not Available
Paraesthesia17.02.06.005--
Peroneal nerve palsy17.09.02.0030.004896%Not Available
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Phlebitis24.05.03.001; 12.02.01.002--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.0030.003831%Not Available
Pollakiuria20.02.02.0070.004896%
Postoperative wound infection12.02.05.011; 11.01.08.008--Not Available
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