Drug Name |
Urokinase |
Drug ID |
BADD_D02320 |
Description |
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943]
Urokinase was granted FDA approval on 16 January 1978.[L12138] |
Indications and Usage |
Urokinase can be used for the treatment of pulminary embolism, coronary artery thrombosis, IV catheter clearance, and venous and arterial blood clots. |
Marketing Status |
Discontinued |
ATC Code |
B01AD04 |
DrugBank ID |
DB00013
|
KEGG ID |
D03341
|
MeSH ID |
D014568
|
PubChem ID |
Not Available
|
TTD Drug ID |
Not Available
|
NDC Product Code |
Not Available |
Synonyms |
Urokinase-Type Plasminogen Activator | Urokinase Type Plasminogen Activator | Plasminogen Activator, Urokinase-Type | U-Plasminogen Activator | U Plasminogen Activator | U-PA | Urinary Plasminogen Activator | Urokinase | Renokinase | Abbokinase | Kidney Plasminogen Activator | Single-Chain Urokinase-Type Plasminogen Activator | Single Chain Urokinase Type Plasminogen Activator |