Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triazolam
Drug ID BADD_D02277
Description Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Indications and Usage For the short-term treatment of insomnia.
Marketing Status Prescription; Discontinued
ATC Code N05CD05
DrugBank ID DB00897
KEGG ID D00387
MeSH ID D014229
PubChem ID 5556
TTD Drug ID D0U3LS
NDC Product Code 0009-0017; 55289-787; 67763-128; 0054-4858; 0009-5188; 50742-645; 59762-3718; 50742-646; 71335-1876; 59762-3717; 50090-4733; 12828-0041; 0054-4859; 43063-996; 50090-0522; 42816-0017; 43353-451; 63629-2956
Synonyms Triazolam | U-33,030 | U 33,030 | U33,030 | Halcion | Trilam | Apo-Triazo | Apo Triazo | Gen-Triazolam | Gen Triazolam
Chemical Information
Molecular Formula C17H12Cl2N4
CAS Registry Number 28911-01-5
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysaesthesia17.02.06.003--
Dysarthria19.19.03.001; 17.02.08.0010.004616%
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.0060.001847%
Dyspnoea22.02.01.004; 02.01.03.002--
Dystonia17.01.03.001--Not Available
Dysuria20.02.02.0020.001847%
Electrocardiogram QT prolonged13.14.05.0040.002770%
Electroencephalogram abnormal13.07.03.001--Not Available
Eosinophil count13.01.06.021--Not Available
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Extrasystoles02.03.02.0030.001847%Not Available
Eye irritation06.04.05.003--Not Available
Fall12.01.08.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling jittery08.01.09.0160.001847%Not Available
Flatulence07.01.04.002--
Fracture15.08.02.001; 12.04.02.0010.001847%
Gait disturbance17.02.05.016; 08.01.02.0020.002770%
Gastric cancer16.13.03.001; 07.21.02.0010.000482%Not Available
Gastrointestinal pain07.01.05.005--
Glaucoma06.03.01.0020.002770%
Glossitis07.14.01.001--Not Available
Glossodynia07.14.02.001--Not Available
Haematocrit13.01.05.017--Not Available
Haemoglobin13.01.05.018--Not Available
Haemorrhage subcutaneous24.07.06.010; 23.06.07.0020.001847%Not Available
Hallucination19.10.02.0020.006463%
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