Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone
Drug ID BADD_D02170
Description Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943]
Indications and Usage Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995]
Marketing Status approved; investigational
ATC Code G03BA03
DrugBank ID DB00624
KEGG ID D00075
MeSH ID D013739
PubChem ID 6013
TTD Drug ID D06XMU
NDC Product Code 0832-1120; 65089-0050; 43598-304; 49884-418; 63629-8455; 63629-9310; 0591-2925; 38779-2936; 43647-568; 43742-1436; 73774-014; 76003-1083; 43742-1242; 0245-0871; 62332-552; 70700-112; 76420-685; 76420-687; 76420-699; 24979-130; 45802-610; 0051-8462; 64380-151; 68180-943; 69097-363; 0591-2363; 0603-7831; 0009-5020; 44132-006; 49452-7658; 64025-0010; 45802-281; 0245-0872; 0023-5992; 63629-2125; 64380-152; 66887-001; 0591-2114; 0591-2924; 0591-2926; 0591-3216; 0832-1121; 51927-0267; 70492-002; 76420-684; 0009-0074; 12875-8248; 22552-0009; 49452-7652; 60592-721; 60870-0251; 16714-967; 17139-562; 63629-2124; 68180-941; 44132-008; 48087-0113; 51552-0029; 42667-5511; 63481-183; 63629-2352; 69238-1013; 0591-3217; 0591-3524; 38779-0163; 38779-2598; 82393-113; 24979-078; 45802-366; 66887-004; 51552-0564; 62991-2150; 76420-686; 16714-969; 45802-754; 49884-510; 62332-488; 69339-158; 0591-2921; 49452-7657; 16714-968; 0023-5990
UNII 3XMK78S47O
Synonyms Testosterone | 17-beta-Hydroxy-4-Androsten-3-one | 17 beta Hydroxy 4 Androsten 3 one | Androtop | Histerone | Sterotate | Sustanon | Androderm | Testoderm | Testolin | Testopel | Testosterone Sulfate | AndroGel | 8-Isotestosterone | 8 Isotestosterone | 17-beta-Hydroxy-8 alpha-4-Androsten-3-one | 17 beta Hydroxy 8 alpha 4 Androsten 3 one | Andropatch | Testim
Chemical Information
Molecular Formula C19H28O2
CAS Registry Number 58-22-0
SMILES CC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Carotid artery thrombosis24.01.04.007; 17.08.01.0250.000091%Not Available
Carpal tunnel syndrome17.09.02.0010.000400%Not Available
Cerebellar infarction24.04.06.007; 17.08.01.0130.000500%Not Available
Cerebral artery occlusion24.04.06.020; 17.08.01.0280.000227%Not Available
Cerebral infarction24.04.06.002; 17.08.01.0040.001772%Not Available
Cerebral ischaemia17.08.01.005; 24.04.06.0030.000227%
Cerebral thrombosis24.01.04.003; 17.08.01.0060.000182%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.055483%
Cerebrovascular disorder24.03.05.002; 17.08.02.0020.000591%Not Available
Cheilitis23.03.03.025; 07.05.01.001--
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.12.02.0030.003508%Not Available
Chills15.05.03.016; 08.01.09.001--
Chronic obstructive pulmonary disease22.03.01.007--Not Available
Clitoral engorgement21.08.02.006--Not Available
Clumsiness17.01.02.0050.000091%Not Available
Coagulopathy01.01.02.0010.000518%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Coronary artery disease24.04.04.006; 02.02.01.0010.005816%Not Available
Coronary artery occlusion24.04.04.013; 02.02.01.006; 12.02.01.0360.000772%Not Available
Coronary artery stenosis12.02.01.037; 24.04.04.017; 02.02.01.0100.000500%Not Available
Coronary artery thrombosis24.01.05.002; 02.02.01.0070.000772%Not Available
Cough22.02.03.001--
Cyst08.03.05.001; 16.02.02.002--Not Available
Depression19.15.01.001--
Depression suicidal19.15.01.004--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Dermatitis bullous23.03.01.002--
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