Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Streptokinase
Drug ID BADD_D02070
Description Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Indications and Usage For the treatment of acute evolving transmural myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thrombosis or emolism and occlusion of arteriovenous cannulae
Marketing Status Not Available
ATC Code B01AD01
DrugBank ID DB00086
KEGG ID D06879
MeSH ID D013300
PubChem ID 9815560
TTD Drug ID D04URO
NDC Product Code Not Available
Synonyms Streptokinase | Streptase | Streptodecase | Kabikinase | Awelysin | Celiase | Distreptase | Kabivitrum | Avelizin
Chemical Information
Molecular Formula C11H19NO2
CAS Registry Number 9002-01-1
SMILES C1CCC(CC1)C2CC(NC2)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Chills15.05.03.016; 08.01.09.001--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Eye swelling06.08.03.003--Not Available
Feeling abnormal08.01.09.014--Not Available
Flushing23.06.05.003; 24.03.01.002; 08.01.03.025--
Guillain-Barre syndrome17.09.01.001; 11.07.01.001; 10.04.10.005--
Haematocrit decreased13.01.05.001--Not Available
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Malaise08.01.01.003--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
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