Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sevelamer
Drug ID BADD_D02012
Description Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Indications and Usage For the control of serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.
Marketing Status Prescription; Discontinued
ATC Code V03AE02
DrugBank ID DB00658
KEGG ID D08512
MeSH ID D000069603
PubChem ID 3085017
TTD Drug ID D03MZQ
NDC Product Code Not Available
Synonyms Sevelamer | GT335-012 | GT335 012 | GT335012 | Sevelamer Hydrochloride | Hydrochloride, Sevelamer | RenaGel | Sevelamer Carbonate | Carbonate, Sevelamer
Chemical Information
Molecular Formula C6H12ClNO
CAS Registry Number 52757-95-6
SMILES C=CCN.C1C(O1)CCl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Constipation07.02.02.0012.233592%
Cough22.02.03.001--
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.0010.628013%
Diverticulitis11.01.07.003; 07.10.02.0010.004937%Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Duodenal ulcer07.04.02.0020.001975%
Duodenal ulcer haemorrhage07.04.02.004; 24.07.02.0200.001975%Not Available
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.0010.141204%
Dysphagia07.01.06.0030.036535%
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Eczema23.03.04.006--
Eosinophilia01.02.04.001--
Eructation07.01.02.0030.003950%
Eye swelling06.08.03.003--Not Available
Faeces discoloured07.01.03.002--Not Available
Faeces hard07.01.03.0030.001975%Not Available
Fat tissue increased08.01.03.0090.001975%Not Available
Fatigue08.01.01.002--
Flatulence07.01.04.0020.202425%
Fluid overload14.05.06.001; 02.05.04.0040.003950%Not Available
Fracture12.04.02.001; 15.08.02.001--
Gangrene24.04.05.003; 23.06.06.001; 11.02.01.0030.001975%Not Available
Gastric haemorrhage24.07.02.007; 07.12.01.001--
Gastric ulcer07.04.03.0020.005925%
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 6 Pages