| Pharmaceutical Information |
| Drug Name |
Secobarbital |
| Drug ID |
BADD_D01997 |
| Description |
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom. |
| Indications and Usage |
For the Short-term treatment of intractable insomnia for patients habituated to barbiturates |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N05CA06 |
| DrugBank ID |
DB00418
|
| KEGG ID |
D00430
|
| MeSH ID |
D012631
|
| PubChem ID |
5193
|
| TTD Drug ID |
D00SJE
|
| NDC Product Code |
Not Available |
| Synonyms |
Secobarbital | Meballymal | Quinalbarbitone | Sebar | Seconal Sodium | Seconal | Secobarbital Sodium | Sodium, Secobarbital |
|
| Chemical Information |
| Molecular Formula |
C12H18N2O3 |
| CAS Registry Number |
76-73-3 |
| SMILES |
CCCC(C)C1(C(=O)NC(=O)NC1=O)CC=C |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Respiratory failure | 22.02.06.002; 14.01.04.003 | - | - | | | Shock | 24.06.02.002 | - | - | Not Available | | Somnolence | 17.02.04.006; 19.02.05.003 | - | - | | | Syncope | 24.06.02.012; 17.02.04.008; 02.01.02.008 | - | - | | | Tension | 19.06.02.005 | - | - | Not Available | | Thinking abnormal | 19.10.03.001; 17.02.05.023 | - | - | Not Available | | Vomiting | 07.01.07.003 | - | - | | | Liver injury | 12.01.02.003; 09.01.07.022 | - | - | Not Available |
|
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|
