Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 63850-7138; 33342-087; 33342-088; 62938-0021; 62938-0022; 62938-0020; 63850-7119; 71335-1352; 62938-0019; 65977-0067
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eructation07.01.02.003--
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Eye burns06.11.01.003; 12.01.04.010--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Eye swelling06.08.03.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Facial pain08.01.08.0120.000691%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.0140.001382%Not Available
Feeling cold08.01.09.0080.000691%Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance17.02.05.016; 08.01.02.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Hallucination19.10.02.002--
Hangover08.01.09.018--Not Available
Headache17.14.01.0010.004837%
Heart disease congenital02.01.01.009; 03.07.07.0010.000691%Not Available
Hepatitis09.01.07.0040.002073%Not Available
Hiccups22.02.04.002; 07.01.06.009--
Hyperacusis17.04.03.003; 04.02.02.001--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.0280.000691%
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.0030.000691%
Hypersomnia19.02.05.001; 17.15.01.001--
Hypertension24.08.02.001--
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