Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Remifentanil hydrochloride
Drug ID BADD_D01923
Description Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Indications and Usage For use during the induction and maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH06
DrugBank ID DB00899
KEGG ID D01177
MeSH ID D000077208
PubChem ID 60814
TTD Drug ID D0T5OX
NDC Product Code 48954-724; 68475-506; 63323-725; 0143-9393; 63323-723; 67457-914; 50683-0550; 43798-761; 68475-507; 67457-198; 12502-5343; 67457-912; 67457-913; 0143-9391; 68475-505; 63323-724; 0143-9392
Synonyms Remifentanil | 3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester | Remifentanil Hydrochloride | Ultiva | Remifentanil Monohydrochloride | GI 87084B | GI87084B | GI-87084B
Chemical Information
Molecular Formula C20H29ClN2O5
CAS Registry Number 132539-07-2
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Hypothermia12.05.03.001; 08.05.01.003--
Hypoxia22.02.02.003--
Ileus07.13.01.001--
Immune system disorder10.02.01.001--Not Available
Laryngospasm22.04.02.002--
Leukocytosis01.02.01.002--
Loss of consciousness17.02.04.004--Not Available
Lymphopenia01.02.02.002--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Muscle twitching15.05.03.005--Not Available
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nasal congestion22.04.04.001--
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Neuromuscular block prolonged17.05.04.005; 12.02.12.004--Not Available
Nightmare19.02.03.003--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oedema14.05.06.010; 08.01.07.006--Not Available
Oliguria20.01.03.004--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Pericarditis02.06.02.001--
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