Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rabeprazole
Drug ID BADD_D01898
Description Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Indications and Usage For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
Marketing Status approved; investigational
ATC Code A02BC04
DrugBank ID DB01129
KEGG ID D08463
MeSH ID D064750
PubChem ID 5029
TTD Drug ID D0KL4J
NDC Product Code 65162-724
UNII 32828355LL
Synonyms Rabeprazole | 2-((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methylsulfinyl)-1H-benzimidazole | Dexrabeprazole | E 3810 | E3810 | Pariet | Rabeprazole Sodium | Sodium, Rabeprazole | 1H-Benzimidazole, 2-(((4-(3-methoxypropoxy)-3-methyl-2-pyridinyl)methyl)sulfinyl)-, Sodium Salt | Aciphex | LY-307640 | LY 307640 | LY307640
Chemical Information
Molecular Formula C18H21N3O3S
CAS Registry Number 117976-89-3
SMILES CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCCCOC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hernia08.01.04.001--Not Available
Herpes simplex23.11.05.004; 11.05.02.001--Not Available
Herpes virus infection11.05.02.008--Not Available
Herpes zoster23.11.05.005; 17.09.03.026; 11.05.02.003--
Hiccups07.01.06.009; 22.12.01.001--
Hyperammonaemia09.01.02.002; 14.10.01.001--Not Available
Hyperchlorhydria07.11.03.001--Not Available
Hypercholesterolaemia14.08.01.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.0280.000521%
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.0030.001145%
Hypertension24.08.02.001--
Hyperthyroidism14.11.01.011; 05.02.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hyperventilation19.01.02.004; 22.02.01.006--Not Available
Hypoaesthesia23.03.03.081; 17.02.06.0230.000833%Not Available
Hypocalcaemia14.04.01.0040.002473%
Hypochromic anaemia01.03.02.004--Not Available
Hypokalaemia14.05.03.0020.001041%
Hypomagnesaemia14.04.02.0010.003124%
Hyponatraemia14.05.04.0020.000521%
Hypotension24.06.03.002--
Hypothyroidism14.11.01.012; 05.02.03.001--
Hypoventilation22.02.01.007--Not Available
Hypoxia22.02.02.003--
Ileal ulcer07.04.06.008--
Immune system disorder10.02.01.001--Not Available
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Influenza like illness08.01.03.010--
The 6th Page    First    Pre   6 7 8 9 10    Next   Last    Total 13 Pages