Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status Prescription
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 59572-504; 59572-503; 68554-0091; 82245-0108; 55111-989; 17337-0068; 65015-893; 68554-0092; 42973-232; 70225-1106; 54893-0038; 59572-501; 59572-502
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ankle fracture12.04.01.005; 15.08.03.005--
Anosmia22.04.03.006; 17.04.04.0010.003474%
Anxiety19.06.02.002--
Aphasia19.21.01.001; 17.02.03.001--
Aphthous ulcer07.05.06.002--Not Available
Appendicitis11.01.07.001; 07.19.01.001--
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis24.04.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.0010.013317%
Arthropathy15.01.01.0030.031266%Not Available
Aspartate aminotransferase increased13.03.01.006--
Aspiration22.02.07.007--
Asthenia08.01.01.0010.196278%Not Available
Asthma22.03.01.002; 10.01.03.0100.022581%Not Available
Ataxia17.02.02.001; 08.01.02.004--
Atrial fibrillation02.03.03.0020.066005%
Atrial flutter02.03.03.003--
Atrioventricular block02.03.01.002--Not Available
Atypical pneumonia22.07.01.010; 11.01.09.0120.002895%Not Available
Azotaemia20.01.01.0010.001158%Not Available
Back disorder15.03.01.0140.016212%Not Available
Back pain15.03.04.0050.081638%
Bacteraemia11.01.11.0010.006369%
Basal cell carcinoma23.08.02.001; 16.03.02.001--Not Available
Benign prostatic hyperplasia21.04.02.001--Not Available
Bladder cancer20.03.04.001; 16.08.01.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blister23.03.01.001; 12.01.06.002--Not Available
Blood albumin decreased13.09.01.001--Not Available
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