Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phenazopyridine
Drug ID BADD_D01745
Description Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA.[L7832] It is still used in various parts of the world. Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or red color, as it is considered an azo dye.[L7829]
Indications and Usage For the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
Marketing Status Not Available
ATC Code G04BX06
DrugBank ID DB01438
KEGG ID D08346
MeSH ID D010621
PubChem ID 4756
TTD Drug ID D00VUL
NDC Product Code 68071-2479; 71335-1805; 68071-2357; 51293-612; 65162-682; 63629-1001; 71335-1399; 55700-283; 63629-9127; 71335-1280; 65162-681; 63629-2029; 71335-2014; 61919-762; 50090-5904; 67296-1212; 63629-8985; 63629-7702; 68071-2583; 63629-2028; 60846-502; 50090-5876; 68788-7981; 63629-7701; 71335-1184; 60846-501; 51293-611; 63629-8986; 68788-7902
Synonyms Phenazopyridine | Azo-Gesic | Azo Gesic | AzoGesic | Azo-Natural | Azo Natural | AzoNatural | Azo-Standard | Azo Standard | AzoStandard | Baridium | UTI Relief | Phenazo | Phenazopyridine Hydrochloride | Hydrochloride, Phenazopyridine | Prodium | Pyridium | Re-Azo | Re Azo | ReAzo | Urogesic | Azo-Dine | Azo Dine | AzoDine | Geridium | Pyridiate
Chemical Information
Molecular Formula C11H11N5
CAS Registry Number 94-78-0
SMILES C1=CC=C(C=C1)N=NC2=C(N=C(C=C2)N)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Glucose-6-phosphate dehydrogenase deficiency01.06.05.001; 14.14.03.001; 03.08.03.001--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hepatotoxicity12.03.01.008; 09.01.07.009--Not Available
Hypersensitivity10.01.03.003--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Meningitis aseptic17.06.03.002; 11.01.03.002--Not Available
Methaemoglobinaemia01.05.01.002--
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Nephropathy toxic20.05.03.002; 12.03.01.010--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Sulphaemoglobinaemia01.05.01.003--Not Available
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
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