| Pharmaceutical Information |
| Drug Name |
Pentobarbital |
| Drug ID |
BADD_D01726 |
| Description |
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) |
| Indications and Usage |
For the short-term treatment of insomnia. |
| Marketing Status |
Discontinued; Prescription |
| ATC Code |
N05CA01 |
| DrugBank ID |
DB00312
|
| KEGG ID |
D00499
|
| MeSH ID |
D010424
|
| PubChem ID |
4737
|
| TTD Drug ID |
D0F0YZ
|
| NDC Product Code |
Not Available |
| Synonyms |
Pentobarbital | Pentobarbitone | Mebubarbital | Etaminal | Ethaminal | Sagatal | Nembutal | Pentobarbital Sodium | Pentobarbital, Monosodium Salt | Monosodium Salt Pentobarbital | Diabutal | Mebumal |
|
| Chemical Information |
| Molecular Formula |
C11H18N2O3 |
| CAS Registry Number |
57-33-0 |
| SMILES |
CCCC(C)C1(C(=O)NC(=O)NC1=O)CC |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Shock | 24.06.02.002 | - | - | Not Available | | Somnolence | 19.02.05.003; 17.02.04.006 | - | - | | | Syncope | 24.06.02.012; 17.02.04.008; 02.01.02.008 | - | - | | | Tension | 19.06.02.005 | - | - | Not Available | | Vomiting | 07.01.07.003 | - | - | | | Liver injury | 12.01.02.003; 09.01.07.022 | - | - | Not Available |
|
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