Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Patiromer
Drug ID BADD_D01686
Description Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate with diethenylbenzene and octa-1,7-diene, combination with D-glucitol. Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.
Indications and Usage For the treatment of hyperkalemia.
Marketing Status Prescription
ATC Code V03AE09
DrugBank ID DB09263
KEGG ID D11037
MeSH ID C568789
PubChem ID Not Available
TTD Drug ID D0Z2YQ
NDC Product Code 53436-252; 53436-084; 53436-168
Synonyms patiromer | Veltassa | RLY 5016 | RLY5016 | RLY-5016
Chemical Information
Molecular Formula Not Available
CAS Registry Number 1260643-52-4
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hallucination19.10.02.002--
Headache17.14.01.001--
Heart rate increased13.14.04.002--Not Available
Hepatic failure09.01.03.002-
Hip fracture15.08.03.001; 12.04.01.001-
Hypercalcaemia14.04.01.003; 05.04.01.002-
Hyperkalaemia14.05.03.001-
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokalaemia14.05.03.002-
Hypomagnesaemia14.04.02.001--
Hypophosphataemia14.04.03.001-
Hypotension24.06.03.002--
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Influenza like illness08.01.03.010-
Insomnia17.15.03.002; 19.02.01.002--
Intestinal ischaemia24.04.08.001; 07.15.02.001-Not Available
Intestinal obstruction07.13.01.002-Not Available
Joint dislocation15.01.07.002; 12.04.02.007-Not Available
Joint swelling15.01.02.004--Not Available
Lip oedema23.04.01.006; 10.01.05.004; 07.05.04.004--Not Available
Localised infection11.01.08.006-Not Available
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003-
Metabolic acidosis14.01.01.003--Not Available
Muscle spasms15.05.03.004-
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001-
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