| Drug Name |
Paroxetine impurity a |
| Drug ID |
BADD_D01682 |
| Description |
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others.[T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.[L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters.[A31914] Because of its potent inhibition of serotonin reuptake, paroxetine is more likely to cause withdrawal effects upon cessation. Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.[A31914] The controlled release formulation was designed to decrease the likelihood of nausea that is sometimes associated with paroxetine.[L7700,L7742] |
| Indications and Usage |
Labeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N06AB05 |
| DrugBank ID |
DB00715
|
| KEGG ID |
D02362
|
| MeSH ID |
D017374
|
| PubChem ID |
3038120
|
| TTD Drug ID |
D06GDY
|
| NDC Product Code |
0615-8174; 50268-643; 54766-907; 61919-322; 66267-721; 68071-1594; 68180-647; 70518-1202; 72241-030; 50268-640; 61919-658; 63187-564; 63629-1840; 68788-7410; 69117-0026; 69367-336; 13107-156; 13107-157; 51655-356; 60760-398; 68788-6870; 70518-0739; 70518-1721; 61919-596; 69117-0025; 70518-0003; 71209-094; 13107-155; 50090-0848; 50090-2143; 53002-1174; 63187-434; 63629-3349; 63739-963; 68382-097; 69117-0024; 69367-337; 70518-2574; 71335-0544; 55289-972; 61919-512; 68382-098; 71209-096; 71335-0321; 58118-0183; 60760-501; 68071-1740; 68180-646; 72241-031; 13107-154; 50268-642; 63187-105; 69117-0027; 69367-335; 70518-3277; 71209-095; 43353-713; 43547-409; 63187-190; 63739-888; 68071-1746; 68071-4997; 68180-645; 68382-001; 70954-319; 71610-056; 0574-0279; 0615-8173; 0615-8359; 68382-099; 70518-2465; 72241-029 |
| Synonyms |
Paroxetine | Aropax | BRL-29060 | BRL 29060 | BRL29060 | FG-7051 | FG 7051 | FG7051 | Paroxetine Acetate | Seroxat | Paroxetine Hydrochloride Anhydrous | Paroxetine Maleate | Paroxetine, cis-(+)-Isomer | Paroxetine, cis-(-)-Isomer | Paroxetine, trans-(+)-Isomer | Paxil | Paroxetine Hydrochloride Hemihydrate | Paroxetine Hydrochloride, Hemihydrate | Paroxetine Hydrochloride |
