Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxymorphone
Drug ID BADD_D01648
Description An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092). On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and abuse risks associated with the product's injectable reformulation.
Indications and Usage For the treatment of moderate-to-severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA11
DrugBank ID DB01192
KEGG ID D08323
MeSH ID D010111
PubChem ID 5284604
TTD Drug ID D02NSF
NDC Product Code 0406-3433
Synonyms Oxymorphone | Oxymorphone Hydrochloride | Oxymorphone HCl | Numorphan | Opana
Chemical Information
Molecular Formula C17H19NO4
CAS Registry Number 76-41-5
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pulmonary function test decreased13.19.01.001--Not Available
Renal impairment20.01.03.0100.005750%Not Available
Intellectual disability19.21.06.001; 17.03.07.001--Not Available
Acute kidney injury20.01.03.0160.020127%
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