Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cellulitis23.09.01.001; 11.02.01.0010.000464%Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Cerebral infarction24.04.06.002; 17.08.01.004--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Cheyne-Stokes respiration22.02.01.024--Not Available
Chills15.05.03.016; 08.01.09.0010.000418%
Choking22.02.05.001--Not Available
Cholecystitis chronic09.03.01.0040.000093%Not Available
Cholelithiasis09.03.01.0020.000325%Not Available
Cholestasis09.01.01.001--Not Available
Chronic obstructive pulmonary disease22.03.01.0070.000157%Not Available
Circadian rhythm sleep disorder19.02.06.002; 17.15.06.0020.000093%Not Available
Circulatory collapse24.06.02.0010.000036%Not Available
Coagulopathy01.01.02.0010.000093%Not Available
Cold sweat23.02.03.002; 08.01.03.0240.000186%Not Available
Colitis ulcerative10.02.01.004; 07.08.01.0050.000139%Not Available
Colon cancer16.13.01.001; 07.21.01.0010.000097%Not Available
Coma17.02.09.0010.001485%Not Available
Compartment syndrome24.04.05.006; 15.05.05.0050.000093%Not Available
Completed suicide19.12.01.001; 08.04.01.0100.001889%Not Available
Compression fracture15.08.02.004; 12.04.02.0080.000093%Not Available
Concussion17.11.01.004; 12.01.10.0050.000186%Not Available
Confusional state19.13.01.001; 17.02.03.0050.001950%
Conjunctivitis11.01.06.012; 06.04.01.0020.000093%
Constipation07.02.02.0010.005060%
Cough22.02.03.001--
Crohn's disease10.02.01.005; 07.08.01.015--Not Available
Crying19.04.02.002; 17.02.05.013; 12.02.11.001; 08.01.03.0050.000325%Not Available
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