Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Ofloxacin
Drug ID BADD_D01598
Description A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Indications and Usage For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
Marketing Status approved
ATC Code J01MA01; S01AE01; S02AA16
DrugBank ID DB01165
KEGG ID D00453
MeSH ID D015242
PubChem ID 4583
TTD Drug ID D03NHW
NDC Product Code 13985-602; 17478-713; 24208-410; 60505-0560; 63187-472; 63187-734; 0404-7189; 68071-2265; 68788-8195; 70756-607; 75834-119; 11980-779; 53002-1604; 53002-2604; 50090-5186; 60505-0363; 70518-2037; 71209-099; 70518-0192; 70518-3573; 59116-1820; 68788-8178; 70518-3710; 71205-420; 53069-0440; 53002-1324; 63187-184; 64980-432; 71209-097; 58032-0090; 24208-434; 68071-2254; 68071-2544; 68071-2834; 75834-112; 75834-120; 68071-3448; 68788-7693; 72189-108; 50090-1346; 63187-662; 64980-515; 63187-268; 63629-8716; 68788-8264; 68788-8449; 71209-098; 59390-140
UNII A4P49JAZ9H
Synonyms Ofloxacin | Ofloxacine | Tarivid | ORF-28489 | ORF 28489 | ORF28489 | DR-3355 | DR 3355 | DR3355 | Hoe-280 | Hoe 280 | Hoe280 | Ofloxacin Hydrochloride | Ru-43280 | Ru 43280 | Ru43280 | DL-8280 | DL 8280 | DL8280
Chemical Information
Molecular Formula C18H20FN3O4
CAS Registry Number 82419-36-1
SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pelvic inflammatory disease21.14.04.001; 11.01.10.006--Not Available
Pertussis22.07.04.002; 11.02.23.001--Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Phobia19.06.03.002--Not Available
Photophobia17.17.02.006; 06.01.01.0040.000183%
Photosensitivity reaction23.03.09.003--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Productive cough22.02.03.0050.000167%
Prostatitis21.09.01.001--Not Available
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Pruritus genital23.03.12.008; 21.10.01.002--Not Available
Pseudomembranous colitis07.19.01.003; 11.02.02.002--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Pyuria20.08.02.016; 11.01.08.043--Not Available
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rash follicular23.03.10.001--Not Available
Rash maculo-papular23.03.13.0040.000250%
Rash papular23.03.13.0170.000083%Not Available
Rash pustular23.03.10.003; 11.01.12.002--
Renal failure20.01.03.0050.000083%Not Available
Respiratory arrest22.02.01.009--Not Available
Rhabdomyolysis15.05.05.0020.000125%
Rhinitis22.07.03.006; 11.01.13.004--
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ADReCS-Target
Drug Name ADR Term Target
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