Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ofloxacin
Drug ID BADD_D01598
Description A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Indications and Usage For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
Marketing Status Prescription; Discontinued
ATC Code J01MA01; S01AE01; S02AA16
DrugBank ID DB01165
KEGG ID D00453
MeSH ID D015242
PubChem ID 4583
TTD Drug ID D03NHW
NDC Product Code 59390-140; 68047-713; 68071-2544; 71205-420; 63187-472; 55111-161; 71209-097; 75834-119; 68071-1588; 68788-7693; 24208-434; 63187-268; 71209-098; 11980-779; 70518-1892; 68071-2254; 68071-1607; 50383-024; 64980-515; 71209-099; 50090-5425; 50090-1090; 58032-0090; 63187-184; 63187-734; 13985-602; 55111-160; 68071-1630; 68071-5150; 63187-662; 68071-2265; 68071-4832; 50090-5186; 53002-1324; 75834-120; 55111-162; 53002-1604; 59116-1820; 50090-5209; 50090-0891; 60505-0363; 53002-2604; 60505-0560; 50090-1346; 50090-5210; 72969-108; 24208-410; 63629-8716; 0404-7189; 61919-931; 75834-112; 17478-713; 72189-108; 53069-0440
Synonyms Ofloxacin | Ofloxacine | Tarivid | ORF-28489 | ORF 28489 | ORF28489 | DR-3355 | DR 3355 | DR3355 | Hoe-280 | Hoe 280 | Hoe280 | Ofloxacin Hydrochloride | Ru-43280 | Ru 43280 | Ru43280 | DL-8280 | DL 8280 | DL8280
Chemical Information
Molecular Formula C18H20FN3O4
CAS Registry Number 82419-36-1
SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neutropenia01.02.03.004--Not Available
Neutrophilia01.02.01.005--Not Available
Nightmare19.02.03.003--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Ocular hyperaemia06.04.05.0040.000398%Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oropharyngeal swelling23.04.01.013; 22.04.05.005; 10.01.05.014; 07.05.04.002--Not Available
Otitis externa11.01.05.003; 04.01.02.001--
Otitis media11.01.05.004; 04.05.01.001--
Overdose12.08.01.003--Not Available
Pain08.01.08.0040.000995%
Pain in extremity15.03.04.010--
Palpitations02.01.02.003--
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.0050.000398%
Paranoia19.05.01.005--Not Available
Pathogen resistance11.01.08.0490.000156%Not Available
Pelvic inflammatory disease21.14.04.001; 11.01.10.006--Not Available
Pertussis22.07.04.002; 11.02.23.001--Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Phobia19.06.03.002--Not Available
Photophobia17.17.02.006; 06.01.01.0040.000398%
Photosensitivity reaction23.03.09.003--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Prostatitis21.09.01.001--Not Available
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
The 6th Page    First    Pre   6 7 8 9 10    Next   Last    Total 10 Pages