Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nizatidine
Drug ID BADD_D01582
Description A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Indications and Usage For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.
Marketing Status Prescription; OTC; Discontinued
ATC Code A02BA04
DrugBank ID DB00585
KEGG ID D00440
MeSH ID D016567
PubChem ID 3033637
TTD Drug ID D0Q9DK
NDC Product Code 55111-310; 55111-311; 60846-301; 68071-1633; 63629-2769; 68462-425; 71335-0086; 63187-249; 0591-3137; 68071-5043; 65162-659; 0591-3138; 55111-011; 72643-018; 68462-426
Synonyms Nizatidine | N-(2-(((2-((Dimethylamino)methyl)-4-thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine | LY-139037 | LY 139037 | LY139037 | Axid
Chemical Information
Molecular Formula C12H21N5O2S2
CAS Registry Number 76963-41-2
SMILES CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hepatocellular injury09.01.07.008--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperuricaemia14.09.01.003--
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Libido decreased21.03.02.005; 19.08.03.001--
Myalgia15.05.02.001--
Nasal congestion22.04.04.001--
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Nervousness19.06.02.003--Not Available
Pain08.01.08.004--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
Sinusitis22.07.03.007; 11.01.13.005--
Somnolence19.02.05.003; 17.02.04.006--
Tension19.06.02.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
Tooth disorder07.09.05.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
The 2th Page    First    Pre   2 3    Next   Last    Total 3 Pages