Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nitroglycerin
Drug ID BADD_D01579
Description Nitroglycerin is a vasodilator drug used for the treatment of chest pain and high blood pressure.[T628,L4429] It was first approved in 2000 and is currently marketed by Pfizer, and other companies, depending on the dosage form.[T628,L4894] Nitroglycerin is available in various forms, including a spray form, sublingual tablet form, intravenous form, extended-release tablet form, and transdermal form. A less commonly known fact is that in addition to treating angina, nitroglycerin is also used in an ointment to treat the pain that accompanies anal fissures. The rectal ointment form of nitroglycerin was approved by the FDA in 1955.[L7096]
Indications and Usage For the prevention of angina
Marketing Status Prescription; Discontinued
ATC Code C01DA02; C05AE01
DrugBank ID DB00727
KEGG ID D00515
MeSH ID D005996
PubChem ID 4510
TTD Drug ID D07YDE
NDC Product Code 59762-4921; 51662-1340; 68071-2260; 28595-550; 60429-839; 0338-1051; 0378-9116; 52584-810; 47781-456; 0904-5495; 50090-4874; 0338-1047; 0220-2291; 43598-895; 0220-2287; 0281-0326; 63629-8829; 71872-7010; 51662-1282; 71872-7201; 70518-0545; 49483-223; 64117-543; 43598-896; 50742-516; 71205-225; 0378-9104; 0220-2283; 0071-0418; 76299-430; 63629-8830; 50742-517; 59762-0489; 49483-222; 0220-2279; 60429-840; 71872-7033; 0404-9928; 0378-9102; 50090-3266; 68428-407; 71205-482; 0220-2290; 50742-514; 0404-9929; 43598-435; 47781-457; 52584-418; 0517-4810; 0904-0643; 45802-210; 68071-4909; 42291-648; 28595-705; 0220-2286; 70518-0105; 50742-515; 50742-518; 0378-9112; 50742-513; 0338-1049; 43598-893; 70518-2910; 0220-2282; 0904-0647; 51662-1386; 68462-638; 28595-120; 68071-1330; 50090-0332; 50090-0133; 59762-3304; 51662-1351; 63187-884; 51662-1244; 68428-100; 68071-1720; 60429-841; 63629-8828; 0220-2293; 0071-0417; 0904-5497; 43598-437; 0904-5496; 43598-894; 68428-050; 47781-458; 0071-0419; 68462-639; 43598-436; 58914-301; 49483-221; 68462-640
Synonyms Nitroglycerin | Glyceryl Trinitrate | Trinitrate, Glyceryl | Nitrolan | Nitrospan | Nitrostat | Perlinganit | Nitrong | Susadrin | Sustac | Sustak | Sustonit | Transderm Nitro | Nitroglyn | Trinitrin | Trinitrolong | Anginine | Dynamite | Gilustenon | Nitrangin | Nitro-Bid | Nitro Bid | NitroBid | Nitro-Dur | Nitro Dur | NitroDur | Nitrocard | Nitroderm | Nitroderm TTS | Nitrol | Tridil
Chemical Information
Molecular Formula C3H5N3O9
CAS Registry Number 55-63-0
SMILES C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ulcer08.03.06.0010.000282%Not Available
Unresponsive to stimuli17.02.05.0310.000564%Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular headache24.03.05.007; 17.14.01.005--Not Available
Vasospasm24.04.02.0020.000282%Not Available
Ventricular extrasystoles02.03.04.0070.000423%Not Available
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.0070.000846%
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Withdrawal hypertension24.08.02.009; 08.06.02.007--Not Available
Mental status changes19.07.01.0010.000282%Not Available
Coronary artery dissection24.02.02.001; 02.02.01.0040.000282%Not Available
Cardiopulmonary failure02.05.01.004; 22.02.06.0040.000282%Not Available
Lymphatic disorder01.09.01.003--Not Available
Drug tolerance08.06.01.003--Not Available
Clonic convulsion17.12.03.008--Not Available
Haemorrhage24.07.01.002--Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.0030.000282%Not Available
Paraesthesia oral17.02.06.008; 07.05.03.0030.000705%Not Available
Vasodilation procedure25.03.01.001--Not Available
Angiopathy24.03.02.007--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.0270.000282%
Cardiac disorder02.01.01.003--Not Available
Infestation23.09.05.001; 11.09.01.001--Not Available
Limb discomfort15.03.04.0140.000282%Not Available
Ischaemia24.04.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
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