Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nevirapine
Drug ID BADD_D01557
Description A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Indications and Usage For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
Marketing Status Prescription; Discontinued
ATC Code J05AG01
DrugBank ID DB00238
KEGG ID D00435
MeSH ID D019829
PubChem ID 4463
TTD Drug ID D0O2EM
NDC Product Code 42571-131; 68554-0044; 65862-932; 31722-505; 0781-5893; 0597-0123; 65162-209; 64380-709; 33342-004; 65862-027; 0378-4050; 0378-4890; 70159-002; 65862-057; 53104-7546; 65862-933; 33342-238; 64220-102; 0597-0047
Synonyms Nevirapine | Nevirapine Hemihydrate | Hemihydrate, Nevirapine | Viramune | BI-RG-587 | BI RG 587 | BIRG587
Chemical Information
Molecular Formula C15H14N4O
CAS Registry Number 129618-40-2
SMILES CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Congenital anomaly03.02.01.001--Not Available
Conjunctivitis11.01.06.012; 06.04.01.002--
Death08.04.01.0010.045978%
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Developmental delay08.01.03.0370.012155%Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug eruption08.01.06.015; 23.03.05.001; 10.01.01.005--Not Available
Drug interaction08.06.03.001--Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Embolism venous24.01.01.0030.007927%Not Available
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Eye pain06.08.03.0020.012155%
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gamma-glutamyltransferase abnormal13.03.01.028--Not Available
Gamma-glutamyltransferase increased13.03.01.011--
Gastroenteritis11.01.07.004; 07.19.03.0010.011098%Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Granulocytopenia01.02.03.003--Not Available
Haemoglobin13.01.05.018--Not Available
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