| Pharmaceutical Information |
| Drug Name |
Naftifine |
| Drug ID |
BADD_D01517 |
| Description |
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. |
| Indications and Usage |
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications. |
| Marketing Status |
Prescription |
| ATC Code |
D01AE22 |
| DrugBank ID |
DB00735
|
| KEGG ID |
D08245
|
| MeSH ID |
C029178
|
| PubChem ID |
47641
|
| TTD Drug ID |
D00HPK
|
| NDC Product Code |
Not Available |
| Synonyms |
naftifine | naftifin | naftifine hydrochloride, (E)-isomer | naftifine hydrochloride | N-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride |
|
| Chemical Information |
| Molecular Formula |
C21H21N |
| CAS Registry Number |
65472-88-0 |
| SMILES |
CN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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|
