Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Minoxidil
Drug ID BADD_D01473
Description A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Indications and Usage For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
Marketing Status Prescription; OTC; Discontinued
ATC Code C02DC01; D11AX01
DrugBank ID DB00350
KEGG ID D00418
MeSH ID D008914
PubChem ID 4201
TTD Drug ID D0Y2CJ
NDC Product Code 51927-2885; 37808-833; 51672-2129; 63981-798; 50383-001; 63981-032; 42291-619; 41250-749; 82269-607; 38779-0574; 49035-202; 69282-002; 43353-342; 40700-0008; 64162-0209; 69968-0030; 25280-007; 71176-781; 59640-000; 21130-819; 41250-428; 42291-618; 11673-919; 0113-1129; 68391-294; 69113-129; 11673-317; 71730-294; 56062-202; 49884-256; 56062-798; 41250-294; 0363-2294; 63486-015; 0591-5643; 0363-2798; 76003-0748; 57483-542; 11822-0202; 51552-0536; 0591-5642; 66219-0004; 69282-001; 71730-798; 49035-294; 68196-032; 51326-160; 11822-0129; 0113-0294; 72764-001; 68196-469; 63629-2232; 79481-0070; 59779-294; 41250-798; 41163-798; 21130-750; 37808-798; 57483-535; 72288-202; 63629-2230; 0009-5056; 63940-032; 56062-294; 30142-798; 68016-382; 71205-490; 68084-204; 59779-202; 46204-0159; 82157-100; 71713-092; 68981-036; 0113-0798; 51552-1334; 0009-5230; 57483-530; 71713-093; 11822-0702; 70550-605; 30142-632; 72484-095; 63940-491; 49035-746; 79974-201; 17337-0027; 0113-7294; 62991-1105; 81653-002; 73277-002; 54236-020; 0113-7202; 80855-201; 37808-202; 11673-431; 82157-200; 11822-0606; 69113-128; 0113-7798; 79572-022; 67438-015; 0363-1129; 0363-0703; 73277-001; 63629-1085; 71290-813; 79903-072; 0113-7129; 65121-101; 0363-7202; 56062-322; 63940-202; 46144-342; 25280-006; 69423-586; 51672-2128; 68196-823; 63629-1086; 11673-798; 63934-007; 71730-202; 11673-189; 63940-385; 0363-0032; 49035-798; 63981-380; 67438-020; 69968-0031; 0113-1032; 63629-2231; 69842-599; 49452-4780; 70550-503; 21130-273; 11673-632; 69968-0089; 72882-094; 53489-386; 11673-707; 65121-102; 68084-205; 72288-294; 37808-404; 11822-1033; 49539-001; 71713-091; 0472-0066; 80813-0022; 65121-562; 69968-0090; 57483-540; 63940-582; 0113-7032; 41250-202; 55301-094; 72764-002; 69842-797; 11822-0798; 63486-016; 49884-257; 71730-129; 11673-382; 21130-163; 59779-798; 53489-387; 30142-719; 11509-0798; 51326-161; 69842-598; 81653-001; 69423-587; 63981-294; 49035-905; 71724-400; 72288-129; 30142-294; 68016-006
Synonyms Minoxidil | Rogaine | Regaine | U 10858 | Loniten
Chemical Information
Molecular Formula C9H15N5O
CAS Registry Number 38304-91-5
SMILES C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
Lymphatic disorder01.09.01.003--Not Available
Alcohol withdrawal syndrome08.06.02.002; 19.07.02.0080.004823%Not Available
Skin burning sensation23.03.03.021; 17.02.06.0090.004823%Not Available
Blood alkaline phosphatase increased13.04.02.004--
Breast disorder21.05.04.004--Not Available
Cardiac disorder02.01.01.003--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Blood disorder01.05.01.004--Not Available
Chorioretinopathy06.09.01.0060.006430%Not Available
Acute kidney injury20.01.03.0160.006430%
Sinus node dysfunction02.03.03.0170.003215%
Occupational asthma22.03.01.024; 10.01.03.0450.004823%Not Available
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