Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Midodrine
Drug ID BADD_D01461
Description An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Indications and Usage For the treatment of symptomatic orthostatic hypotension (OH).
Marketing Status Prescription; Discontinued
ATC Code C01CA17
DrugBank ID DB00211
KEGG ID D08220
MeSH ID D008879
PubChem ID 4195
TTD Drug ID D02XJY
NDC Product Code 0615-8358
Synonyms Midodrine | Midodrin | Midodrine Hydrochloride | Midodrine Monohydrochloride | Monohydrochloride, Midodrine | ProAmatine | Amatine | ST-1085 | ST 1085 | ST1085 | Gutron | Midon
Chemical Information
Molecular Formula C12H18N2O4
CAS Registry Number 42794-76-3
SMILES COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Anxiety19.06.02.002--
Aphthous ulcer07.05.06.002--Not Available
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bradycardia02.03.02.002--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state19.13.01.001; 17.02.03.005--
Dermatitis23.03.04.002--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Erythema multiforme23.03.01.003; 10.01.03.015--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing23.06.05.003; 24.03.01.002; 08.01.03.025--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Hair disorder23.02.06.003--Not Available
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hypertension24.08.02.001--
Insomnia19.02.01.002; 17.15.03.002--
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