Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mianserin
Drug ID BADD_D01454
Description A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Indications and Usage For the treatment of depression.
Marketing Status approved; investigational
ATC Code N06AX03
DrugBank ID DB06148
KEGG ID D08216
MeSH ID D008803
PubChem ID 4184
TTD Drug ID D0R6RO
NDC Product Code Not Available
UNII 250PJI13LM
Synonyms Mianserin | Mianserin Hydrochloride | Hydrochloride, Mianserin | Mianserin Monohydrochloride | Monohydrochloride, Mianserin | Tolvon | Lerivon | Org GB 94
Chemical Information
Molecular Formula C18H20N2
CAS Registry Number 24219-97-4
SMILES CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lethargy08.01.01.008; 19.04.04.004; 17.02.04.003--
Leukopenia01.02.02.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Myalgia15.05.02.001--
Nasal congestion22.04.04.001--
Nervous system disorder17.02.10.001--Not Available
Neuroleptic malignant syndrome15.05.04.015; 12.03.01.003; 08.05.01.005; 17.05.02.003--Not Available
Neutropenia01.02.03.004--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pancytopenia01.03.03.003--Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Suicidal ideation19.12.01.003--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Torsade de pointes02.03.04.005--Not Available
Tremor17.01.06.002--
Vertigo17.02.12.002; 04.04.01.003--
Weight increased13.15.01.006--
Musculoskeletal discomfort15.03.04.001--Not Available
Depressive symptom19.15.02.003--Not Available
Restless legs syndrome17.02.07.008; 15.05.03.012--Not Available
Angiopathy24.03.02.007--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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