Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylergonovine maleate
Drug ID BADD_D01429
Description A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Indications and Usage For the prevention and control of excessive bleeding following vaginal childbirth
Marketing Status Prescription; Discontinued
ATC Code G02AB01
DrugBank ID DB00353
KEGG ID D00680
MeSH ID D008755
PubChem ID 5281072
TTD Drug ID D05AHE
NDC Product Code 51662-1556; 0054-0639; 16571-735; 17478-501; 51991-144; 63629-2074; 0093-3655; 43386-140; 0517-0740; 27437-050; 40032-140; 60687-410; 63704-004; 50090-4536
Synonyms Methylergonovine | Methylergometrine | Methylergobasin | Methylergometrin | Methylergonovine Maleate | Methylergometrine Maleate | Methergine | Méthergin | Methergin
Chemical Information
Molecular Formula C24H29N3O6
CAS Registry Number 57432-61-8
SMILES CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C.C(=CC(=O)O)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Arterial spasm24.04.02.011--Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.005--Not Available
Bradycardia02.03.02.002--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Haematuria24.07.01.047; 20.02.01.006--
Hallucination19.10.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Muscle spasms15.05.03.004--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Palpitations02.01.02.003--
Rash23.03.13.001--Not Available
Tachycardia02.03.02.007--Not Available
Thrombophlebitis24.01.02.001--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Vomiting07.01.07.003--
Water intoxication19.07.03.004; 14.05.06.004; 05.03.03.003--Not Available
Peripheral arterial occlusive disease24.04.03.010--Not Available
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