Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methoxsalen
Drug ID BADD_D01420
Description A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Indications and Usage For the treatment of psoriasis and vitiligo
Marketing Status Prescription; Discontinued
ATC Code D05AD02; D05BA02
DrugBank ID DB00553
KEGG ID D00139
MeSH ID D008730
PubChem ID 4114
TTD Drug ID D08SKH
NDC Product Code 51927-1685; 62350-0049; 62991-2896; 42249-1002; 64067-216; 64380-752; 51927-0162; 72643-011
Synonyms Methoxsalen | Xanthotoxin | 8-Methoxypsoralen | 8 Methoxypsoralen | Ammoidin | Deltasoralen | Dermox | Geroxalen | Meladinina | Methoxa-Dome | Methoxa Dome | Oxsoralen | Méladinine | Meladinine | Oxsoralen-Ultra | Oxsoralen Ultra | Puvalen | Ultramop | 8-MOP | 8 MOP | 8MOP | Meloxine
Chemical Information
Molecular Formula C12H8O4
CAS Registry Number 298-81-7
SMILES COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pruritus23.03.12.001--
Psoriasis23.03.14.002; 10.02.01.036--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.0010.015426%Not Available
Pyrexia08.05.02.0030.009255%
Rash23.03.13.001--Not Available
Rash vesicular23.03.13.009--Not Available
Sepsis11.01.11.0030.002146%
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin hyperpigmentation23.05.01.003--
Skin hypopigmentation23.05.02.003--
Squamous cell carcinoma16.16.01.0020.002057%Not Available
Sunburn23.03.09.007; 12.05.02.001--Not Available
Systemic lupus erythematosus23.03.02.006; 15.06.02.003; 10.04.03.004--Not Available
Tenderness08.01.08.005--Not Available
Tension19.06.02.005--Not Available
Thrombosis24.01.01.0060.004114%Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.0030.006170%
Wheezing22.03.01.0090.003085%
Deep vein thrombosis24.01.02.0030.002057%Not Available
Haemorrhage24.07.01.0020.003085%Not Available
Inflammation08.01.05.007--Not Available
Ill-defined disorder08.01.03.049--Not Available
Disease progression08.01.03.0380.001073%
Disease recurrence08.01.03.0500.000805%Not Available
Solar lentigo23.05.01.013--Not Available
Device related infection11.01.08.018; 08.07.01.005--
Acute graft versus host disease12.02.09.002; 10.02.01.0280.000805%Not Available
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