Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meperidine
Drug ID BADD_D01384
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D08343
MeSH ID D008614
PubChem ID 4058
TTD Drug ID D00UYE
NDC Product Code Not Available
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H21NO2
CAS Registry Number 57-42-1
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.0010.118037%
Neurotoxicity17.02.10.002; 12.03.01.011--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Oxygen saturation decreased13.02.01.0040.005208%Not Available
Pain08.01.08.004--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Palpitations02.01.02.003--
Paralysis17.01.04.0040.003472%Not Available
Paranoia19.05.01.005--Not Available
Phlebitis24.05.03.001; 12.02.01.002--
Pruritus23.03.12.0010.034717%
Pyrexia08.05.02.003--
Rash23.03.13.0010.050339%Not Available
Respiratory arrest22.02.01.0090.000906%Not Available
Respiratory depression17.02.05.047; 22.02.01.010--Not Available
Respiratory distress22.02.01.0120.003472%Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Swelling08.01.03.0150.017358%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Unresponsive to stimuli17.02.05.0310.006943%Not Available
Urinary retention20.02.02.011--
Urticaria23.04.02.001; 10.01.06.0010.076377%
Vertigo17.02.12.002; 04.04.01.003--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.0030.151018%
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