Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meloxicam
Drug ID BADD_D01374
Description Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis.[A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Indications and Usage For symptomatic treatment of arthritis and osteoarthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AC06
DrugBank ID DB00814
KEGG ID D00969
MeSH ID D000077239
PubChem ID 54677470
TTD Drug ID D0G7FJ
NDC Product Code 61919-469; 38779-2746; 67296-1317; 29300-125; 68788-7904; 63629-2020; 71610-583; 0615-8124; 70518-1828; 65841-051; 43063-396; 43063-401; 72865-138; 69344-205; 80425-0043; 61919-434; 71610-580; 68071-4987; 71610-544; 42708-093; 65862-097; 70518-3023; 43063-395; 50090-5339; 51552-1377; 50436-1125; 17373-1157; 56125-750; 70954-077; 70859-007; 69344-206; 17373-1158; 72969-045; 60760-419; 60760-448; 43353-979; 80425-0045; 51869-0008; 76282-153; 65841-050; 70934-010; 60592-994; 72865-137; 59349-0003; 53002-1537; 50090-5861; 0615-8040; 53747-006; 68071-1919; 53069-0790; 50090-0986; 67296-1817; 50436-1124; 68071-3030; 71335-0406; 51407-610; 45865-360; 68382-050; 35356-808; 69097-159; 67296-0583; 54458-964; 50090-5340; 68180-502; 51407-611; 61442-126; 50090-0985; 61442-127; 71205-923; 43353-127; 68382-051; 80425-0041; 71518-001; 67296-0823; 68225-112; 16571-776; 50268-526; 51869-0007; 52119-003; 71610-542; 76282-152; 55289-618; 67296-1250; 49452-4402; 71335-1888; 68981-032; 60760-404; 70954-076; 42708-007; 68462-141; 68180-501; 65862-098; 70518-0039; 53002-2535; 71205-924; 54458-965; 80425-0042; 53104-7574; 68071-1993; 50090-4896; 70518-0200; 43353-038; 0395-8154; 68071-1994; 68071-2184; 60687-199; 53002-1535; 80425-0083; 65862-223; 68180-189; 68788-1701; 0597-0029; 70518-2631; 0597-0030; 64380-715; 68788-9418; 50268-525; 71610-380; 68462-140; 63629-3328; 29300-124; 69097-158; 76420-043; 51655-731; 63629-2019; 58118-1158; 68788-7726; 53002-2537; 71335-1956; 63629-7966; 64380-716; 71335-1618; 65841-004; 63187-082; 62938-0026; 63187-083; 71610-516; 68180-188; 16571-777; 70518-1299; 51927-0032; 70518-0031; 49999-869; 80425-0044; 76420-039; 51655-577; 63629-3248; 55289-272; 70518-0171; 22365-116; 58624-0430
Synonyms Meloxicam | Miloxicam | Parocin | Mobic | Mobicox | Mobec | Masflex | Movicox | Reumoxicam | Uticox | Movalis
Chemical Information
Molecular Formula C14H13N3O4S2
CAS Registry Number 71125-38-7
SMILES CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Mass08.03.05.0030.000110%Not Available
Melaena24.07.02.013; 07.12.02.0040.000513%Not Available
Memory impairment19.20.01.003; 17.03.02.003--
Migraine24.03.05.003; 17.14.02.0010.000073%Not Available
Mood altered19.04.02.007--Not Available
Mouth ulceration07.05.06.004--Not Available
Muscle spasms15.05.03.004--
Musculoskeletal pain15.03.04.0070.000073%
Myalgia15.05.02.0010.000183%
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nephrotic syndrome20.05.01.0020.000147%
Nervousness19.06.02.003--Not Available
Nodal rhythm02.03.02.0060.000073%Not Available
Ocular hyperaemia06.04.05.0040.000110%Not Available
Oedema14.05.06.010; 08.01.07.0060.000073%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.000183%
Oesophageal ulcer07.04.05.0020.000073%
Oesophagitis07.08.05.0010.000110%
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.01.02.0030.000110%
Pancreatitis07.18.01.001--
Paraesthesia17.02.06.0050.000183%
Pemphigoid23.03.01.004; 10.04.02.0020.000110%Not Available
Penile swelling21.12.01.0060.000073%Not Available
Peptic ulcer07.04.07.0010.000073%Not Available
Pericardial haemorrhage24.07.01.013; 02.06.01.0030.000073%Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photosensitivity reaction23.03.09.003--
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