Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mefenamic acid
Drug ID BADD_D01368
Description A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Indications and Usage For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Marketing Status approved
ATC Code M01AG01
DrugBank ID DB00784
KEGG ID D00151
MeSH ID D008528
PubChem ID 4044
TTD Drug ID D05FTJ
NDC Product Code 80425-0306; 51552-1367; 58747-0601; 62250-677; 62350-0015; 49452-4398; 52935-0008; 51927-4457; 0276-0509; 38779-0669; 42571-258; 68180-185; 22365-117
UNII 367589PJ2C
Synonyms Mefenamic Acid | Acid, Mefenamic | Mefenaminic Acid | Pontal | Contraflam | Coslan | Parkemed | Ponstan Forte | Ponsyl | Dysman | Mefac | Mefacit | Nu-Mefenamic | Nu Mefenamic | Pinalgesic | PMS-Mefenamic Acid | PMS Mefenamic Acid | Ponalar | Ponalgic | Ponmel | Ponstan | Ponstel | Mefic | Apo-Mefenamic | Apo Mefenamic
Chemical Information
Molecular Formula C15H15NO2
CAS Registry Number 61-68-7
SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug tolerance08.06.01.0030.002974%Not Available
Protein urine present13.13.02.006--Not Available
Haemorrhage24.07.01.002--Not Available
Weight abnormal13.15.01.016--Not Available
Epidermal necrosis23.03.03.035--Not Available
Urine output increased13.13.03.002--Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Appetite disorder19.09.01.002; 14.03.01.004--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Gastrointestinal ulcer07.04.04.002--Not Available
Ill-defined disorder08.01.03.049--Not Available
Adjustment disorder19.23.01.0010.002974%Not Available
Adverse drug reaction08.06.01.009--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Renal impairment20.01.03.010--Not Available
Cystitis noninfective20.03.02.001--
Choroidal effusion06.09.01.0080.002974%Not Available
Gastrointestinal inflammation07.08.03.007--Not Available
Bone marrow failure01.03.03.005--
Autoimmune haemolytic anaemia10.04.01.005; 01.06.01.004--Not Available
Perforation08.01.03.058--Not Available
Fixed eruption23.03.05.008; 10.01.01.037; 08.01.06.0250.002974%Not Available
Therapeutic product effect incomplete08.06.01.052--Not Available
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